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Systems Biology for Traditional Chinese Medicine by Guoan Luo, Yiming Wang, Qionglin Liang, Qingfei Liu

By Guoan Luo, Yiming Wang, Qionglin Liang, Qingfei Liu

Emphasizing the concord of the human physique with the surroundings, conventional chinese language drugs (TCM) has advanced over hundreds of thousands of years. it's a systemic idea derived from medical adventure, the philosophy of holism and systematology, and the idea that guy is a vital part of nature.

Systems Biology for standard chinese language medication describes how the newest equipment in structures biology might be utilized to TCM, offering a complete source for the modernization and development of TCM in addition to normal drug discovery efforts. it's the first complete paintings to suggest a system-to-system examine technique to check the interplay among TCM and the human physique and its purposes in drug examine and development.

Using 3 well known conventional chinese language medicines—Shuanglongfang, Qingkailing, and Liushenwan—as examples, the authors set forth case examples demonstrating how to define fabric teams, practice efficacy screenings, and behavior safeguard reviews of TCM. The ebook also:

Describes the mechanisms of TCM on the molecular and structures degrees utilizing chemomics, genomics, proteomics, metabolomics, and bioinformatics
Places sleek medical applied sciences in the context of TCM, aiding drug researchers increase experimental designs and strategies
Illustrates how a platforms biology strategy is suitable with TCM's conventional, holistic healing suggestions and remedy modalities
Presents subject matters of present curiosity, reminiscent of built-in worldwide platforms biology and the appliance of chemometrics learn to natural medicines
This ebook not just opens a brand new pathway for the continuing improvement of TCM, but in addition for structures biology. additionally, it fosters collaboration and dialogue between japanese and Western scientists via using platforms biology to TCM.

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Systems Biology for Traditional Chinese Medicine

Emphasizing the concord of the human physique with the surroundings, conventional chinese language drugs (TCM) has developed over hundreds of thousands of years. it's a systemic idea derived from scientific adventure, the philosophy of holism and systematology, and the assumption that guy is an essential component of nature.

Systems Biology for standard chinese language drugs describes how the newest tools in structures biology will be utilized to TCM, offering a entire source for the modernization and development of TCM in addition to common drug discovery efforts. it's the first finished paintings to suggest a system-to-system study method to review the interplay among TCM and the human physique and its functions in drug examine and development.

Using 3 renowned conventional chinese language medicines—Shuanglongfang, Qingkailing, and Liushenwan—as examples, the authors set forth case examples demonstrating how to define fabric teams, practice efficacy screenings, and behavior defense reviews of TCM. The publication also:

Describes the mechanisms of TCM on the molecular and structures degrees utilizing chemomics, genomics, proteomics, metabolomics, and bioinformatics
Places sleek medical applied sciences in the context of TCM, assisting drug researchers increase experimental designs and strategies
Illustrates how a structures biology technique is suitable with TCM's conventional, holistic healing options and remedy modalities
Presents themes of present curiosity, corresponding to built-in international structures biology and the appliance of chemometrics study to natural medicines
This publication not just opens a brand new pathway for the ongoing improvement of TCM, but in addition for platforms biology. additionally, it fosters collaboration and dialogue between jap and Western scientists by way of employing platforms biology to TCM.

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A complicated TCM formula can be divided into several effective component groups (there may be hundreds of chemical components) to illustrate the chemical substance basis of the compatibility of TCM formula with the aid of pharmacodynamics. As a result, we put forward a research strategy including using modern separation methods to extract effective component groups, fingerprint for qualification, indicate components for quantification, and identify the integrity of effective component groups and pharmacodynamics.

In addition, the cooking of the drugs in prescription follows an order; otherwise, the best efficacy of the formula cannot be achieved. Principles such as “relieving the exterior syndrome and then catharizing,” “supplying deficiency and then expelling excess,” and “ascending the clear and descending the turbid” are typical time-order principles in TCM formulas. (4) Dynamic principles of TCM formulas: In TCM theory, the balance (or imbalance) of Yin and Yang are regarded as an orderly (or disorderly) state.

They emphasized the adjustment of chills and heat, complementary of Yin and Yang, the combination of nutrition and purgation, and the compatibility of promoting and control. (1) Combination of cold and heat medication: This kind of treatment can be used for a variety of syndromes. For example, in the formula of Banxiaxiexin decoction, Banxia (Pinelliae Rhizoma) is pungent and warm and can be used to downbear counterflow to suppress vomiting, as a Jun herb. Dried ginger is very hot and can cure cold syndromes.

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