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100 Questions in Cardiology by Diana Holdright, Hugh Montgomery

By Diana Holdright, Hugh Montgomery

(BMJ Books) UCL Hospitals, London, united kingdom. greater than a hundred questions are replied through major cardiologists. functional consultant to administration of advanced occasions. For practitioners and citizens. Softcover.

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They may interfere with the absorption of other drugs so should be taken either one hour before or four hours after other therapeutic agents. The resins theoretically may interfere with the absorption of fat soluble vitamins and folic acid but this is not a major problem in practice. However, perhaps with increasing indication of the role of homocysteine as a risk factor, folic acid supplements might be recommended in patients on resins. 24 100 Questions in Cardiology 13 Is there a role for prescribing antioxidant vitamins to patients with coronary artery disease?

At present there are only two intervention studies in patients with coronary artery disease available to guide therapeutic decisions. The CHAOS study1 used 400 or 800 IU/day while the ATBC study2 used 50 IU/day. Both studies showed that vitamin E does not save lives in patients with coronary artery disease and that it may increase the number of deaths. Both studies also agree that non-fatal myocardial infarctions are reduced significantly, by 38% in the ATBC study and by 77% in the CHAOS study, with a 53% reduction in combined events in the latter study.

12, September 2000. uk) 3 Oler A, Whooley MA, Oler J. Grady D. Adding heparin to aspirin reduces the incidence of myocardial infarction and death in patients 276: 811–15. with unstable angina. JAMA 1996;2 4 Cohen M, Demers C, Gurfinkel EP et al. A comparison of lowmolecular weight heparin with unfractionated heparin for unstable coronary artery disease: Efficiency and Safety of Subcutaneous Enoxaparin in Non-Q-Wave Coronary Events (ESSENCE) Study 337: 447–52. Group. N Engl J Med; 1997;3 100 Questions in Cardiology 45 23 Under what circumstances should the patient with unstable angina undergo PTCA or CABG?

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